Propolis Activity Factor Using Multivariate Data Analysis for Propolis From Different Climatic Zones

Propolis contains resinous material collected by honeybees from plants, and has a plethora of biological activities. The location of propolis collection influences its chemical composition, resulting in variations in biological activity. The present study was designed to analyse the relationship of propolis to geographic location, chemical composition and biological activity. We examined selected flavonoids and phenolics for their individual concentration as well as total content and biological activities i.e. anti-microbial and anti-oxidant activity by applying multiple regression analysis. We observed that, strong correlation between the phenolics and flavonoids for anti-microbial and anti-oxidant activity, respectively. Higher levels of cinnamates were observed in propolis from tropical regions with better anti-microbial potential, whereas temperate propolis with higher levels of flavonoids exhibited better antioxidant potential. We also observed that, climatic zone-based propolis activity factor approach helps to cater the best possible biological application of propolis.
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